Cortical Processes During Walking Post-stroke

Completed

• Conditions: Walking, Difficulty; Stroke, Acute

• Registration Number: NCT05710029
• Lead Sponsor: University of Florida

Brief Summary

The study aims to use novel mobile imaging techniques with high-density electroencephalography (EEG) to quantify cortical processes synchronized to the biomechanics of walking. Here, the study has two aims - the primary aim is to quantify the cortical processes that contribute to gait dysfunction early post-stroke, and the second aim is to determine how cortical processes are mediated by mechanical assistance during early gait training post-stroke.

Participants will wear an electroencephalography (EEG) cap to measure brain activity and other non-invasive physiological sensors. Participants will be asked to perform different tasks, such as walking at different speeds and walking with different levels of body weight support.

Detailed Description

This study will recruit 15 subacute post-stroke individuals and 15 age-matched neurotypical individuals between the age of 18-80 years old.

Study Timeline

• Study First Submitted: 2023-01-10
• Study First Submitted QC: 2023-01-24
• Study First Posted: 2023-02-02
• Study Start: 2023-05-01
• Primary Completion: 2024-06-30
• Study Completion: 2024-06-30
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-26
• Last Update Posted: 2025-04-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Brain activity during walking measured by EEG	through study study completion, an average of 2 years	Differences in brain activity during walking between people post-stroke and neurotypical individuals

Trial Locations

Locations (1)

University of Florida; 🇺🇸 Gainesville, Florida, United States