General Anesthetic Mode and Postoperative Complications

Completed

• Conditions: Anesthesia
• Interventions: Combination Product: inhalation or propofol ,epidural or general anesthesia, remifentanil or sufentanil

• Registration Number: NCT03335579
• Lead Sponsor: Peking University First Hospital

Brief Summary

The relationship between anesthetic medication and postoperative major cardiac and cerebral complications will be studied using logistic regression model.

Detailed Description

The study group try to find out if there is a connection between the use of different anesthetic methods with different narcotic drugs and postoperative major cardiac and cerebral complications.

Study Timeline

• Study Start: 2016-12-31
• Primary Completion: 2017-08-01
• Study Completion: 2017-10-10
• Study First Submitted: 2017-10-30
• Status Verified: 2017-11
• Study First Submitted QC: 2017-11-03
• Last Update Submitted: 2017-11-03
• Study First Posted: 2017-11-07
• Last Update Posted: 2017-11-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50000

Inclusion Criteria

• non-cardiac surgery, with age> = 18 years old, ASA grade I-IV, under general anesthesia

Exclusion Criteria

• non-general anesthesia, without the use of target-controlled infusion of remifentanil or sufentanil, absence of intraoperative or perioperative information.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
non-MACE	inhalation or propofol ,epidural or general anesthesia, remifentanil or sufentanil	patients without major postoperative cardiac or cerebral complications
MACE	inhalation or propofol ,epidural or general anesthesia, remifentanil or sufentanil	patients with major postoperative cardiac or cerebral complications

Primary Outcome Measures

Name	Time	Method
Major cardiac complication	90 days after surgery	major cardiac event