NL-OMON54804招募中3 期
Triple therapy prevention of Recurrent Intracerebral Disease EveNts Trial - TRIDENT
The George Institute for Global Health - Australia0 个研究点目标入组 25 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. Adults (>=18 years) with a history stroke due to primary intracerebral
- •haemorrhage (ICH) confirmed by brain imaging, 2. Clinically stable, as judged
- •by investigator, 3. Two resting systolic BP (SBP) levels, measured 5 minutes
- •apart in the range 130-160mmHg recorded in a seated position., 4. Provision of
- •written informed consent.
排除标准
- •1. Taking an ACE inhibitor antihypertensive drug that cannot be switched to any
- •of the following alternatives:, - telmisartan 20 or 40mg, amlodipine 2.5 or
- •5mg, indapamide 1.25, or;, - an equivalent class (angiotensin receptor blocker,
- •calcium channel blocker, or thiazide-like diuretic), or;, - a beta-blocker, 2.
- •Contraindication to any of the study medications, in the context of currently
- •prescribed BP lowering medication, 3. Unlikely/unable to complete the study
- •procedures and/or follow-up, 4. Females of child bearing age and capability,
- •who are pregnant or breast-feeding, or those not using adequate contraception,
- •5. Any condition that in the opinion of the responsible physician or
- •investigator that renders the patient unsuitable for the study (e.g. severe
- •disability (ie modified Rankin Scale [mRS] score of 4-5] or significant memory
- •or behavioural disorder or hyperkalaemia and/or hyponatremia, defined by local
- •lab criteria)
研究者
相似试验
进行中（未招募）
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Triple therapy prevention of Recurrent Intracerebral Disease EveNts TrialPatients with a history of acute stroke due to Intracranial Haemorrhage with mild to moderately high blood pressure.MedDRA version: 21.1Level: PTClassification code 10019016Term: Haemorrhagic strokeSystem Organ Class: 10029205 - Nervous system disordersEUCTR2016-003724-23-NLThe George Institute for Global Health, University of New South Wales4,200
进行中（未招募）
1 期
Triple therapy prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT)Patients with a history of acute stroke due to Intracranial Haemorrhage with mild to moderately high blood pressure.MedDRA version: 21.1Level: PTClassification code 10019016Term: Haemorrhagic strokeSystem Organ Class: 10029205 - Nervous system disordersEUCTR2016-003724-23-GBThe George Institute for Global Health, University of New South Wales1,500
已完成
3 期
Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts TrialIntracerebral Haemorrhage (ICH)HypertensionNCT02699645The George Institute1,671
终止
3 期
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终止
不适用
Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial Magnetic Resonance Imaging Sub-studyCerebral Small Vessel DiseasesIntracerebral HemorrhageStrokeHypertensionVascular DementiaNCT03783754The George Institute4