Sensitization to Animal Allergens and Allergic Symptoms During Exposure to Animal Allergens in Korean Veterinary Researcher
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 135
- Locations
- 1
- Primary Endpoint
- Skin reactivity to animal allergen in skin prick test
Study Overview
Brief Summary
The investigators will evaluate sensitization to animal allergens and allergic symptom during contacting animal allergens in Korean veterinary researchers who attend their annual conference.
The investigators will compare sensitization to animal allergen and other clinical and occupational factors between subjects who suffer from allergic symptom during contacting animal and those who do not.
Detailed Description
The investigators will visit annual conference of Korean veterinary researchers.
After informed consent, Korean veterinary researchers who attend their conference and agree to enrollment into this study will be asked to respond to questionnaires regarding their gender, age, underlying allergic diseases, family history of allergic diseases, occupation and it's duration, contact animal and contact duration. Subjects will also be requested to report allergic symptom, causal animal and situation of contact including veterinary service, animal experiment, pet ownership, and ingestion if subjects suffer from allergic symptom when subjects contact animal.
Then, subjects will also be asked to undergo skin prick test for animal allergens including chicken feather and ten mammal epithelia as well as cow's milk, and hen's egg, four fish flesh and seven animal meats.
subjects will be divided into two group, subjects who suffer from allergic symptom during contacting animal and those who do not. Between two groups, sensitization to animal allergens as well as other demographic and occupational factors including gender, age, underlying allergic diseases, family history of allergic diseases, occupation and it's duration, contact animal and contact duration will be compared.
Study Design
- Study Type
- Observational
- Observational Model
- Ecologic Or Community
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 19 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Veterinary researchers attending their annual conference
Exclusion Criteria
- •Veterinary researchers who receive medication including antihistamine (H1 and H2 blocker), systemic glucocorticosteroid which can effect on the result of skin prick test
- •Veterinary researchers who do not want to participate in this study
Outcomes
Primary Outcomes
Skin reactivity to animal allergen in skin prick test
Time Frame: on the day of survey (day 1)
Mean diameter of wheal for animal allergen in skin prick test
Secondary Outcomes
- Contact animal(on the day of survey (day 1))
- Underlying allergic disease(on the day of survey (day 1))
- Family history of allergic disease(on the day of survey (day 1))
- Occupation(on the day of survey (day 1))
- Causal animal(on the day of survey (day 1))
- Allergic symptom during contacting animal(on the day of survey (day 1))
- Duration of occupation(on the day of survey (day 1))
- Contact time(on the day of survey (day 1))
- Contact situation(on the day of survey (day 1))
Investigators
Sang Min Lee
Assistant professor
Gachon University Gil Medical Center