The Effect of Laparoscopic Surgery on Ovarian Reserve According to Cyst Types

Not Applicable

Completed

• Conditions: Ovarian Cysts
• Interventions: Procedure: Laparoscopic cystectomy

• Registration Number: NCT05054946
• Lead Sponsor: Ege University

Brief Summary

The aim of our study is to compare the effect of laparoscopic ovarian cystectomy on ovarian reserve in terms of different cyst types.

Detailed Description

Participants who will be treated surgically for ovarian cysts will be included in the study. Anti-Mullerian Hormone (AMH) levels of the participants will be investigated before the surgery and 6 months after the surgery. All surgeries will be performed under general anesthesia laparoscopically. After histopathological evaluation, the participants will be divided into three groups; Group 1: Endometrioma, Group 2: Mature cystic teratoma (Dermoid cyst) and Group 3: Serous or mucinous cystadenoma.

A total of fifty-five women will be included in the study.

Study Timeline

• Study First Submitted: 2021-09-19
• Study First Submitted QC: 2021-09-19
• Study First Posted: 2021-09-23
• Study Start: 2021-10-01
• Status Verified: 2022-09
• Primary Completion: 2022-09-01
• Study Completion: 2022-09-01
• Last Update Submitted: 2022-09-03
• Last Update Posted: 2022-09-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 55

Inclusion Criteria

• no ovarian surgery before

Exclusion Criteria

• Endocrinological pathologies
• Suspicion of malignancy in preoperative laboratory and ultrasonographic evaluations
• Detection of malignancy in histopathological examination

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Mature cystic teratoma (dermoid cyst)	Laparoscopic cystectomy	Participants who will have mature cystic teratoma (dermoid cyst) after histopathological evaluation.
Endometrioma	Laparoscopic cystectomy	Participants who will have endometrioma after histopathological evaluation.
Serous or mucinous cystadenoma	Laparoscopic cystectomy	Participants who will have serous or mucinous cystadenoma after histopathological evaluation.

Primary Outcome Measures

Name	Time	Method
Change in AMH Level	6 months	AMH levels of the participants will be investigated before the surgery and 6 months after the surgery.

Trial Locations

Locations (1)

Ege University Hospital; 🇹🇷 İzmir, Turkey