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A comparison of different round masks for intermittent positive pressure ventilation in preterm infants prior to intubatio

Not Applicable
Recruiting
Conditions
Prematurity
Reproductive Health and Childbirth - Complications of newborn
Respiratory - Other respiratory disorders / diseases
Registration Number
ACTRN12614000709640
Lead Sponsor
Dr Lorraine McGrory
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
128
Inclusion Criteria

Inpatient preterm infants less than 33 weeks post menstrual age requiring mask intermittent positive pressure ventilation before an elective intubation attempt with premedication.

Exclusion Criteria

1. Infants in the delivery room or operating theatre who require endotracheal intubation will not be eligible for entry to this study.

2. Infants with a congenital anomaly of their face which may affect the ability of a mask to create a seal will be excluded.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Difference in leak measured between the mask and the infant’s face between the control and intervention groups.<br><br>A Florian Respiratory Function monitor (Acutronic Medical Systems, Zug, Switzerland) will be used to measure inflating pressures and gas flow via a flow sensor between the mask and the Neopuff. Tidal volumes, and expiratory leak will be measured by the flow sensor. Expiratory leak will be calculated from the volume of gas that does not return back through the flow sensor on expiration, expressed as a percentage of the inspired volume.<br><br>Spectra software (Grove Medical, London, UK) will record the leak, tidal volumes and delivered pressures[Measurements will be taken at the time positive pressure ventilation is administered]
Secondary Outcome Measures
NameTimeMethod
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