Biological characteristics of sensitization characterization in patients with chronic colitis

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: Not specified

Inclusion Criteria

Patients with chronic colitis observation group: (1) chronic colitis diagnostic criteria of mild and moderate patients (that is, clinical manifestations of repeated abdominal pain, diarrhea loose stool (or constipation) , stool does not contain or only a small amount of blood, mucus, no or mild systemic symptoms: colonoscopy can be seen local congestion, edema or scattered erythema, erosion; colonic mucosa pathological examination showed chronic inflammatory changes)(2) gender is not limited, age 18-65 years; (3) willing to participate in the trial and signed informed consent; note: Patients who met the above three criteria were included in the study. The healthy subjects were as follows: (1) no chronic colitis or gastrointestinal disease, (2) no gender limitation, 18-65 years old, (3) willing to participate in the trial and sign the informed consent form; Note: Patients who met the above 3 criteria were included in this study.

Exclusion Criteria

(2) previous myocardial infarction, severe heart failure, valvular heart disease, serious arrhythmias, primary cardiomyopathy, blood diseases; Patients with severe cerebrovascular disease, pregnancy, lactation, mental illness, intestinal tuberculosis, bacterial dementia, radiation colitis, malignant tumor, etc. (5) the patients with bleeding tendency or scar constitution, blood diseases, (6) the patients with skin ulcer or severe infection in the sensitive parts, (7) the patients who participated in other clinical trials. Note: any compliance with any of the above provisions shall be excluded. Healthy controls: (1) patients with previous myocardial infarction, severe heart failure, valvular heart disease, severe arrhythmias, primary cardiomyopathy, blood disorders, and other severe cerebrovascular disease; (2) pregnant women, lactating women and those with mental diseases who can not cooperate, (3) patients with intestinal tuberculosis, bacillary dysentery and malignant tumor, (4) patients with fever symptoms that affect heat sensitivity detection, (3) patients with intestinal tuberculosis, bacillary dysentery and malignant tumor (5) patients with skin diseases affecting shape-sensitive detection; (6) patients with skin ulcer or severe infection at the sensitive site; (7) patients with bleeding tendency or scar constitution; (8) patients who participated in other clinical trials. Note: Patients who meet any of the above criteria will be excluded.