Evaluation of a Clinical Prototype Near-InfraRed Fluorescence (NIRF) Imaging Device for Sentinel Lymph Node (SLN) Detection in Breast Cancer: a Technical Feasibility Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- breast cancer, sentinel lymph node, intraoperative imaging, image-guided surgery
- Sponsor
- Department of Surgery, University Medical Center Groningen
- Enrollment
- 10
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Intraoperative identification of sentinel lymph nodes by near-infrared fluorescence imaging in patients with breast cancer. Tagaya N, Yamazaki R, Nakagawa A, Abe A, Kiyoshige H, Kubota K, Oyama T. Am J Surg 2008;195:850-853.
- Evaluation of breast lymphatic pathways with indocyanine green fluorescence imaging in patients with breast cancer. Ogasawara Y, Ikeda H, Takahashi M, Karasaki K, Doihara H. World J Surg 2008;32:1924-1929.
- Imaging of lymph flow in breast cancer patients after microdose administration of a near-infrared fluophore: Feasibility study. Sevick-Muraca EM, Sharma R, Rasmussen JC, Marshall MV, Wendt JA, Pham HQ, Bonefas E, Houston JP, Sampath L, Adams KE, Blachard DK, Fischer RE, Chiang SB, Elledge R, Mawad ME. Radiology 2008; 246: 734-741.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients with operable invasive breast cancer stage (T1\-2N0\-1 – stage I and II) proven by histology on a biopsy.
Exclusion Criteria
- •1\. Pregnant women.
- •2\. Significant renal (creatinine \>, cardiac, or pulmonary disease (ASA III\-IV).
Outcomes
Primary Outcomes
Not specified