Proteinuria in Pre and Post Transplant
- Conditions
- Proteinuria
- Registration Number
- NCT01094327
- Lead Sponsor
- University of Miami
- Brief Summary
Patients with focal segmental glomerulosclerosis (FSGS) who progress rapidly to end stage renal disease (ESRD) are at highest risk for development of recurrence of proteinuria following kidney transplantation. This study will look at serum specimens pre and post transplant, as well as kidney transplant specimens pre and post reperfusion to identify where the defects has occured that results in recurrence of proteinuria in a given kidney transplant.
- Detailed Description
This study will retrospectively review patient's medical records for protein in the urine, blood creatinine and kidney biopsy results. Also character of the fluid used to flush the kidney before transplant will be analyzed.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 100
- Kidney transplant recipients
- Pediatric males and females up to the age of 25 years old.
- Transplant recipients other than kidney
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Explain mechanisms behind the development of proteinuria in patients immediately after receiving a kidney transplant through study completion, an average of 5 years chart review
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Miami Miller School of Medicine Transplant Clinic
🇺🇸Miami, Florida, United States