Evaluation of Recipients With and Without Proteinuria, Pre and Post Kidney Transplantation
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Explain mechanisms behind the development of proteinuria in patients immediately after receiving a kidney transplant
研究概览
简要总结
Patients with focal segmental glomerulosclerosis (FSGS) who progress rapidly to end stage renal disease (ESRD) are at highest risk for development of recurrence of proteinuria following kidney transplantation. This study will look at serum specimens pre and post transplant, as well as kidney transplant specimens pre and post reperfusion to identify where the defects has occured that results in recurrence of proteinuria in a given kidney transplant.
详细描述
This study will retrospectively review patient's medical records for protein in the urine, blood creatinine and kidney biopsy results. Also character of the fluid used to flush the kidney before transplant will be analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 25 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Kidney transplant recipients
- •Pediatric males and females up to the age of 25 years old.
排除标准
- •Transplant recipients other than kidney
结局指标
主要结局
Explain mechanisms behind the development of proteinuria in patients immediately after receiving a kidney transplant
时间窗: through study completion, an average of 5 years
chart review
次要结局
未报告次要终点
研究者
George W. Burke
Professor of Surgery
University of Miami