CtDNA After Chemotherapy in Elderly Patients With Acute Leukemia

Recruiting

• Conditions: Acute Leukemia

• Registration Number: NCT04157569
• Lead Sponsor: Navy General Hospital, Beijing

Brief Summary

This study will monitor CtDNA After Chemotherapy in Elderly Patients With AL

Detailed Description

This study will use droplet digital PCR (ddPCR) method to quantify peripheral blood plasma mutant allele frequency (MAF) in elderly acute leukemia patients after chemotherapy to evaluate the clinical value of CtDNA .

Study Timeline

• Study First Submitted: 2019-11-04
• Study Start: 2019-11-05
• Study First Submitted QC: 2019-11-06
• Study First Posted: 2019-11-08
• Status Verified: 2020-02
• Last Update Submitted: 2020-02-24
• Last Update Posted: 2020-02-25
• Primary Completion: 2024-12-31
• Study Completion: 2029-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Written informed consent
• Male
• not pregnant female
• patients >=60 years old
• Diagnosis of acute leukemia

Exclusion Criteria

• Pregnancy
• HIV positive
• patients >=100 years old

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cumulative incidence of relapse(CIR)	through study completion, an average of 1 year	cumulative incidence of relapse

Secondary Outcome Measures

Name	Time	Method
overall survival (OS)	through study completion, an average of 2 years	overall survival

Trial Locations

Locations (1)

Navy General Hospital; 🇨🇳 Beijing, China