Clinical study to evaluate the efficacy and safety of curcumin, combination of curcumin and diclofenac in comparison with diclofenac alone in patients with osteoarthritis of the knee

Not Applicable

Completed

• Conditions: Osteoarthritis; Musculoskeletal Diseases

• Registration Number: ISRCTN10074826
• Lead Sponsor: City Care Accident Hospital

Brief Summary

2019 results in https://www.ncbi.nlm.nih.gov/pubmed/30975196 (added 15/04/2019) 2020 results in https://www.ncbi.nlm.nih.gov/pubmed/32311961 (added 22/04/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2013-01-15
• Study Start: 2017-11-29
• Last Update Posted: 4 May 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 139

Inclusion Criteria

1. Subjects of both sexes between 38 and 65 years of age
2. OA in at least one knee joint (ACR classification for knee OA) confirmed by X ray
3. A minimum pain VAS score > 4 on walking in one or both knees during the 24 hours preceding recruitment
4. Duration – minimum 3 months to 2 years with no joint deformities
5. Patient ambulant and requiring treatment with anti- inflammatory drugs
6. Patient willing to give washout period of 3-7 days
7. Patient willing to give written informed consent and willing to comply with the trial protocol
8. Patients with knee osteoarthritis.

Exclusion Criteria

There is no exclusion criteria.

Study & Design

• Study Type: Interventional
• Study Design: Not specified