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Clinical Trials/ISRCTN10074826
ISRCTN10074826
Completed
未知

A randomized, single-blind, comparative, clinical study to evaluate theefficacy and safety of curcumin, combination of curcumin and diclofenac in comparison with diclofenac alone in patients with osteoarthritis of the knee

City Care Accident Hospital0 sites139 target enrollmentNovember 29, 2017

Overview

Phase
未知
Intervention
Not specified
Conditions
Osteoarthritis
Sponsor
City Care Accident Hospital
Enrollment
139
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

2019 results in https://www.ncbi.nlm.nih.gov/pubmed/30975196 (added 15/04/2019) 2020 results in https://www.ncbi.nlm.nih.gov/pubmed/32311961 (added 22/04/2020)

Registry
who.int
Start Date
November 29, 2017
End Date
January 15, 2013
Last Updated
5 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
City Care Accident Hospital

Eligibility Criteria

Inclusion Criteria

  • 1\. Subjects of both sexes between 38 and 65 years of age
  • 2\. OA in at least one knee joint (ACR classification for knee OA) confirmed by X ray
  • 3\. A minimum pain VAS score \> 4 on walking in one or both knees during the 24 hours preceding recruitment
  • 4\. Duration – minimum 3 months to 2 years with no joint deformities
  • 5\. Patient ambulant and requiring treatment with anti\- inflammatory drugs
  • 6\. Patient willing to give washout period of 3\-7 days
  • 7\. Patient willing to give written informed consent and willing to comply with the trial protocol
  • 8\. Patients with knee osteoarthritis.

Exclusion Criteria

  • There is no exclusion criteria.

Outcomes

Primary Outcomes

Not specified

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