NCT00131170CompletedPhase 4
Paravertebral Block for Breast Surgery
Conditions
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- University of Aarhus
- Enrollment
- 90
- Locations
- 2
- Primary Endpoint
- Nausea and vomiting 2 hours postoperatively, and 1 and 2 days postoperatively
Study Overview
Brief Summary
The effect of paravertebral block in combination with general anaesthesia is studied in a double blind fashion.
Detailed Description
Patients having surgery for breast cancer receive a paravertebral blockade at C8-Th4 with either Naropin 0.5% or saline. General anaesthesia is then provided with laryngeal mask intubation, propofol infusion and fentanyl i.v. as needed. The effect on postoperative pain ([VAS] and fentanyl PCA doses taken) and postoperative nausea and vomiting is recorded.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Double
Eligibility Criteria
- Ages
- 18 Years to 85 Years (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Breast surgery
Exclusion Criteria
- •Infections
- •Coagulation disorder
Outcomes
Primary Outcomes
Nausea and vomiting 2 hours postoperatively, and 1 and 2 days postoperatively
Time Frame: 2 days
Secondary Outcomes
- Dosage of analgesic(1 day)
Investigators
Study Sites (2)
Loading locations...
Similar Trials
Completed
Not Applicable
Single Versus Multiple Injection Ultrasound Guided Paravertebral BlocksBreast NeoplasmsAnesthesiaNCT02852421Lawson Health Research Institute70
Completed
Not Applicable
Thoracic Spinal Anesthesia in Awake Breast SurgeryBreast CancerNCT03319511Alaa Mazy70
Unknown
Not Applicable
Thoracic Paravertebral Block Anesthesia for Breast Cancer SurgeryBreast NeoplasmsBreast Neoplasm FemaleCancer, BreastBreast CancerNCT05711030Ciusss de L'Est de l'Île de Montréal68
Completed
Phase 1
Three-level Injection Paravertebral Block vs General Anesthesia in MastectomyRadical MastectomyNCT02065947Ramathibodi Hospital60
Completed
Not Applicable
Paravertebral Block for Postoperative Analgesia in Children Undergoing Lateral Incision Cardiac Surgery With CBPPostoperative PainNCT06312904Chinese Academy of Medical Sciences, Fuwai Hospital100