The effect of two kinds of triggering with GnRh agonist in antagonist protocol
Phase 2
- Conditions
- Triggering with different doses of GnRh a in PCO patients.Female infertility, unspecifiedN97.9
- Registration Number
- IRCT20181211041930N1
- Lead Sponsor
- Yazd University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 120
Inclusion Criteria
PCOS women based on Rotterdam criteria who were candidate for ART
Serum estradiol level more than 3000 pg/ml on triggering day
Ovarian stimulation with GnRH antagonist protocol
Age between 20-38 years
Body Mass Index > 18 and < 30
Exclusion Criteria
Sever endometriosis
Sever male factor infertility
Uterine anomaly
Metabolic disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of mature oocytes (MII). Timepoint: After oocyte retrieval. Method of measurement: Counting mature oocyte under microscopy.;Number of 2PNs. Timepoint: 16 hours After fertilization. Method of measurement: Counting 2PNs under microscopy.;OHSS developing. Timepoint: Days 4 and 7 post oocyte pick-up. Method of measurement: Measuring ovarian size, presence of free fluid in Douglas.
- Secondary Outcome Measures
Name Time Method Embryos quality and embryo count. Timepoint: 48 hours after fertilization. Method of measurement: Assessment under microscopy by embryologist.