PRIMARY: postoperative biomarker measurements after coronary bypass surgery; towards an improved understanding and definition of the concepts of periprocedural myocardial injury and infarction - PRIMARY

Medisch Universitair Ziekenhuis Maastricht0 sites143 target enrollmentTBD

Overview

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

2 years ago

Study Type

Observational invasive

Sponsor

Medisch Universitair Ziekenhuis Maastricht

•\- Adult patients (\>18 years of age).
•\- Surgery preceded by a heart\-team discussion, in which the patient is planned
•for multivessel CABG, receiving more than one graft (i.e., more than only left
•internal mammary artery \[LIMA] to left anterior descending artery \[LAD]).
•\- Isolated on\-pump planned multivessel CABG (defined as using cardiopulmonary
•bypass and cardioplegic arrest).
•\- Able and willing to provide written informed consent.
•\- Elective or urgent surgery (defined as either planned surgery, or a surgical
•procedure without which the patients cannot leave the hospital before the
•surgery is performed24\).

•\- Non\-adult patients (\<18 years of age)
•\- Emergency surgery (defined as within 24 hours of indication and not waiting
•until the following working day24\).
•\- Recent acute coronary syndromes (including ST\-elevation myocardial infarction
•\[STEMI] and non\-STEMI \[NSTEMI], recent defined as \<14 days prior to surgery).
•\- Patients with contraindications to undergo cardiac magnetic resonance imaging
•(including claustrophobia and CMR\-incompatible implants).
•\- Prior adverse reactions to gadolinium\- or iodine\-based contrast agents.
•\- Moderate\-severely compromised renal function (estimated glomerular filtration
•\[eGFR] \<45mL/min/kg)