跳至主要内容
临床试验/NL-OMON56115
NL-OMON56115尚未招募不适用

PRIMARY: postoperative biomarker measurements after coronary bypass surgery; towards an improved understanding and definition of the concepts of periprocedural myocardial injury and infarction - PRIMARY

Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 143 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
143

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • - Adult patients (>18 years of age).
  • - Surgery preceded by a heart-team discussion, in which the patient is planned
  • for multivessel CABG, receiving more than one graft (i.e., more than only left
  • internal mammary artery [LIMA] to left anterior descending artery [LAD]).
  • - Isolated on-pump planned multivessel CABG (defined as using cardiopulmonary
  • bypass and cardioplegic arrest).
  • - Able and willing to provide written informed consent.
  • - Elective or urgent surgery (defined as either planned surgery, or a surgical
  • procedure without which the patients cannot leave the hospital before the
  • surgery is performed24).

排除标准

  • - Non-adult patients (<18 years of age)
  • - Emergency surgery (defined as within 24 hours of indication and not waiting
  • until the following working day24).
  • - Recent acute coronary syndromes (including ST-elevation myocardial infarction
  • [STEMI] and non-STEMI [NSTEMI], recent defined as <14 days prior to surgery).
  • - Patients with contraindications to undergo cardiac magnetic resonance imaging
  • (including claustrophobia and CMR-incompatible implants).
  • - Prior adverse reactions to gadolinium- or iodine-based contrast agents.
  • - Moderate-severely compromised renal function (estimated glomerular filtration
  • [eGFR] <45mL/min/kg)
  • - In clinical heart failure upon admission for surgery.
  • - Pregnant or breast-feeding patients

研究者

发起方
Medisch Universitair Ziekenhuis Maastricht

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