NL-OMON56115Not yet recruitingNot Applicable
PRIMARY: postoperative biomarker measurements after coronary bypass surgery; towards an improved understanding and definition of the concepts of periprocedural myocardial injury and infarction - PRIMARY
Medisch Universitair Ziekenhuis Maastricht0 sites143 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 143
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •- Adult patients (>18 years of age).
- •- Surgery preceded by a heart-team discussion, in which the patient is planned
- •for multivessel CABG, receiving more than one graft (i.e., more than only left
- •internal mammary artery [LIMA] to left anterior descending artery [LAD]).
- •- Isolated on-pump planned multivessel CABG (defined as using cardiopulmonary
- •bypass and cardioplegic arrest).
- •- Able and willing to provide written informed consent.
- •- Elective or urgent surgery (defined as either planned surgery, or a surgical
- •procedure without which the patients cannot leave the hospital before the
- •surgery is performed24).
Exclusion Criteria
- •- Non-adult patients (<18 years of age)
- •- Emergency surgery (defined as within 24 hours of indication and not waiting
- •until the following working day24).
- •- Recent acute coronary syndromes (including ST-elevation myocardial infarction
- •[STEMI] and non-STEMI [NSTEMI], recent defined as <14 days prior to surgery).
- •- Patients with contraindications to undergo cardiac magnetic resonance imaging
- •(including claustrophobia and CMR-incompatible implants).
- •- Prior adverse reactions to gadolinium- or iodine-based contrast agents.
- •- Moderate-severely compromised renal function (estimated glomerular filtration
- •[eGFR] <45mL/min/kg)
- •- In clinical heart failure upon admission for surgery.
- •- Pregnant or breast-feeding patients
Investigators
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