Effect of Soleus Muscle Push Ups on Oxidative Stress and Inflammatory Markers, Soleus Endurance, and Adipocytokines Between Type 2 Diabetic, Overweight/Obese and Normal Weight Individuals.

Not Applicable

Not yet recruiting

• Conditions: Diabete Type 2; Overweight; Obesity
• Interventions: Other: Soleus Muscle Push Up Exercise; Other: Other Exercise

• Registration Number: NCT06450847
• Lead Sponsor: University of Sharjah

Brief Summary

The study aims to investigate the impact of Soleus Push Ups (SPU) on Soleus Muscle endurance, Oxidative Stress Markers, Inflammatory markers and Adipocytokines among people in the United Arab Emirates. This will be a pre-post intervention study with participants divided into three groups: Lean normal metabolic profile, metabolically healthy overweight/obese, and patients with Type 2 Diabetes Mellitus. Assessment of anthropometry and body composition, Soleus Muscle Endurance, blood tests for Inflammatory Markers, Oxidative Stress Markers, and Adipocytokines will be conducted pre and post-intervention.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-05
• Study First Submitted: 2024-05-22
• Study Start: 2024-06
• Study First Submitted QC: 2024-06-04
• Last Update Submitted: 2024-06-04
• Study First Posted: 2024-06-10
• Last Update Posted: 2024-06-10
• Primary Completion: 2024-09
• Study Completion: 2024-10

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

• Residents of UAE, both males and females
• Ages 20-50 years
• Uncomplicated Type 2 Diabetic on meds,
• Normal lean BMI
• Overweight and Obese

Exclusion Criteria

• Recent orthopedic surgery in the LLs
• Pain in the LLs starting from Hips to Ankle.
• Presence of Varicose Veins in the LLs
• Present History of any cardiovascular condition
• Pregnant females
• Morbid Obesity
• Diabetics undergoing Insulin therapy only
• Smokers and alcohol consumption

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Interventional group	Soleus Muscle Push Up Exercise	-
Control group	Other Exercise	-

Primary Outcome Measures

Name	Time	Method
Adipocytokine levels in the blood	3 months	Measured in μg/ml, using blood test by specialized personnel

Secondary Outcome Measures

Name	Time	Method
Soleus Muscle endurance through Heel Raise Test. • Inflammatory and Oxidative Stress markers through blood sample.	3 months	Measured as a number, in repetitions. Detailed procedure described previously.