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Clinical Trials/NCT07347795
NCT07347795
Not yet recruiting
Not Applicable

Blood Flow Restriction Training and Hand Grip Strength in Hemiparetic CP

Cairo University1 site in 1 country40 target enrollmentStarted: February 20, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
40
Locations
1
Primary Endpoint
Hand grip strength measured using a handheld dynamometer

Overview

Brief Summary

The study aims to investigate the effect of blood flow restriction (BFR) training exercises on the hand grip strength of children with hemiparetic cerebral palsy. Hand grip strength is a vital component of motor function and is often severely compromised in children with hemiparetic CP, which can significantly impact their daily activities and quality of life. Blood flow restriction (BFR) training is a novel exercise technique where a cuff or band is used to partially occlude blood flow during low-intensity resistance exercises. This method has been shown to stimulate muscle growth and strength gains similar to those achieved through high-intensity strength training, without the need for high loads. Given the unique physiological challenges faced by children with hemiparetic CP, BFR training could provide an effective alternative to traditional strength training methods.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
6 Years to 12 Years (Child)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age will range from 6-12 years
  • Diagnosed with hemiparetic cerebral palsy (right or left side).
  • According to Modified Ashwer scale, has grade 1 or 1+ grade
  • Children with the ability to understand and follow verbal commands and instructions used during training and tests

Exclusion Criteria

  • Any contraindications to exercise, such as moderate or severe spasticity, orthopedic deformities, or other serious health conditions.

Arms & Interventions

Control group

Active Comparator

The control group performs traditional hand grip strengthening exercises, focusing on similar exercises but without blood flow restriction. Both groups participate in a similar frequency and duration of training, with a gradual increase in repetitions over the 8 weeks

Intervention: control group (Behavioral)

Study group

Experimental

Intervention: Blood Flow Restriction Training Exercises group (Device)

Outcomes

Primary Outcomes

Hand grip strength measured using a handheld dynamometer

Time Frame: 8 weeks

Hand grip strength of the affected hand will be assessed using a calibrated handheld dynamometer. The maximum voluntary grip force will be recorded in kilograms (kg). Three trials will be performed, and the highest value will be used for analysis.

muscle thickness at the midpoint of the forearm flexor muscles

Time Frame: 8 weeks

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Reham Saeed Alsakhawi

Principal Investigator

Cairo University

Study Sites (1)

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