Effect of Sheep Ghee on Lipid Profile and High-sensitivity C-reactive Protein: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- HDL cholesterol
研究概览
简要总结
Normal volunteers were randomly received Sheep ghee or sunflower oil, and before and after the study lipid profile and HS-CRP were measured.
详细描述
During outpatient clinic visits, potentially eligible individuals were screened for enrollment according to the inclusion and exclusion criteria.
Patients were randomly allocated into the treatment and control groups via the blocked randomization method.
The control group received a normal diet for eight weeks with 10 g of sunflower oil. In the treatment group, sunflower oil was replaced with 10 g of sheep ghee.
50 patients in each group were enrollment. Patients' information, including demographic data and the serum levels of fasting blood sugar (FBS), LDL, HDL, triglyceride (TG), and hs-CRP, were recorded in datasheets twice: once before treatment with sheep ghee and once eight weeks later.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
盲法说明
random allocation, open label
入排标准
- 年龄范围
- 20 Years 至 76 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy adults, seeking outpatient visit at professor kojuri cardiology clinic
排除标准
- •any history of ischemic heart disease (IHD),
- •coronary artery bypass grafting (CABG)
- •percutaneous intervention (PCI)
- •peripheral vascular diseases
- •use of anti-hyperlipidemic agents
- •unwillingness to participate.
- •Need of tight hyperlipidemia control.
结局指标
主要结局
HDL cholesterol
时间窗: 2 months
Serum HDL in mg/dl
LDL cholesterol
时间窗: 2 months
serum LDL level in mg/dl
total cholesterol
时间窗: 2 months
serum total cholesterol in mg/dl
HS-CRP
时间窗: 2 months
HS-CRP level in picogram/dl
次要结局
- adverse effect(2 months)
研究者
Javad Kojuri
professor
Shiraz University of Medical Sciences