The Aerobic and Cognitive Training System to Improve Cognition
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Arizona
- Enrollment
- 74
- Primary Endpoint
- Change from baseline in cognitive function during dual-task test at 12 weeks
Study Overview
Brief Summary
This study will determine the effects of simultaneous exercise and cognitive training on cognitive function in healthy older adults. Specifically, this study will compare the use of a tablet-based cognitive training system while exercising with exercise alone, cognitive training alone, and a neutral control condition on cognition.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Other
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 60 Years to 74 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Generally healthy, age 60-74, and a written statement from their primary care physician indicating that they are able to participate in the 12-week exercise program.
Exclusion Criteria
- •Subjects will be excluded from participating in the study if they express significant concerns about their memory or declines in other cognitive abilities, if they are not English speaking, or if they have histories of significant major neurological, psychiatric, or medical disorder or injury that would affect cognitive function.
Arms & Interventions
Simultaneous exercise and cognitive training
Participants in this arm will engage in a 12-week intervention that combines physical exercise and cognitive tablet-based training. This intervention involves use of an exercise bicycle while engaging in cognitive tasks on a tablet computer three times per week.
Intervention: Simultaneous exercise and cognitive training (Behavioral)
Exercise training
Participants in this arm will engage in a 12-week exercise intervention that involves use of an exercise bicycle three times per week.
Intervention: Exercise training (Behavioral)
Cognitive training
Participants in this arm will engage in a 12-week intervention that involves cognitive tablet-based training three times per week.
Intervention: Cognitive Training (Behavioral)
Neutral Video
Participants in this arm will engage in a 12-week intervention that involves watching neutral videos on a tablet computer three times per week.
Intervention: Neutral video (Behavioral)
Outcomes
Primary Outcomes
Change from baseline in cognitive function during dual-task test at 12 weeks
Time Frame: Baseline and 12-weeks
Performance on serial subtraction during dual-task walking.
Secondary Outcomes
- Change from baseline in stride velocity variability during dual-task test(Baseline, 6 weeks, 12 weeks)
- Change from baseline in stride length during dual-task test(Baseline, 6 weeks, 12 weeks)
- Change from baseline in stride duration during dual-task test(Baseline, 6 weeks, 12 weeks)
- Change from baseline in stride velocity during dual-task test(Baseline, 6 weeks, 12 weeks)
- Change from baseline in stride duration variability during dual-task test(Baseline, 6 weeks, 12 weeks)
- Change from baseline in stride length variability during dual-task test(Baseline, 6 weeks, 12 weeks)
- Change from baseline in cognitive function during dual-task test at 6 weeks(Baseline and 6-weeks)