NCT00073151已完成2 期
A Phase II Study of ABT-751 in Patients With Non-Small Cell Lung Cancer Refractory to Taxane Regimens
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- Abbott
- 入组人数
- 30
- 试验地点
- 24
- 主要终点
- Objective Response Rate in subjects with NSCLC
研究概览
简要总结
The purpose of the study is to determine if ABT-751 will decrease tumors, and determine how long the tumor shrinkage can be maintained in patients with non-small cell lung cancer. Patients will receive ABT-751 by mouth daily for 21 days. Patients will be off drug for 7 days before starting the next cycle of drug.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Objective Response Rate in subjects with NSCLC
时间窗: 1 year
次要结局
- Survival(2 years)
- Time to Tumor Progression (TTP)(1 year)
- Toxicities associated with treatment administration(1 year)
研究者
研究点 (24)
Loading locations...
相似试验
已完成
2 期
A Study of ABT-751 in Patients With Recurrent Breast Cancer After Taxane (Taxol or Taxotere) Therapy.Breast CancerNCT00063102Abbott40
已完成
2 期
A Study of ABT-751 in Patients With Colorectal CancerColorectal CancerNCT00073138Abbott40
已完成
2 期
A Study of ABT-751 in Patients With Renal Cell CancerRenal Cell CancerNCT00073112Abbott60
已完成
1 期
Study of ABT-751 in Patients With Refractory Hematologic MalignanciesHematological MalignanciesNCT00047489M.D. Anderson Cancer Center32
已完成
2 期
ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous TreatmentDisseminated NeuroblastomaRecurrent NeuroblastomaNCT00436852Children's Oncology Group92