Predicting fluid responsiveness using the mini fluid challenge and pulse contour cardiac output measurements

Not Applicable

Completed

• Conditions: Postoperative mechanically ventilated cardiac surgery patients; Circulatory System

• Registration Number: ISRCTN37554354
• Lead Sponsor: Department of Intensive Care Medicine, Leiden University Medical Center

Brief Summary

2018 results in https://pubmed.ncbi.nlm.nih.gov/29367093/ (added 12/05/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2014-12-01
• Study Start: 2015-08-04
• Last Update Posted: 24 May 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

Patients undergoing elective coronary artery bypass grafting or valve repair

Exclusion Criteria

1. Previous myocardial infarction
2. Congestive heart failure
3. Aortic aneurysm
4. Extensive peripheral arterial occlusive disease
5. Postoperative valvular insufficiency
6. Artificial pacing and use of a cardiac assist device

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The area under the curve, positive and negative predictive value of COm and COli for the prediction of fluid responsiveness.

Secondary Outcome Measures

Name	Time	Method
Predictive capabilities of mini fluid challenges from 50 to 500 ml.