Cold oxygenated machine preservation of aged renal donation after cardiovascular death transplants
Not Applicable
Completed
- Conditions
- Machine perfusion preservation techniques of kidney graftsInjury, Occupational Diseases, Poisoning
- Registration Number
- ISRCTN32967929
- Lead Sponsor
- niversity of Oxford (UK)
- Brief Summary
2020 results in https://pubmed.ncbi.nlm.nih.gov/33220737/ (added 23/11/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 197
Inclusion Criteria
Donors:
1. All potential consecutive Maastricht category III DCD donors aged 50 years or older from the collaborating donor regions
Recipient:
1. At least 18 years old
2. Listed for renal transplantation due to end stage renal disease
3. Willingness to comply with the protocol procedures for the duration of the study
Exclusion Criteria
Donor:
1. An aortic patch too small for a reliable connection
2. Too many renal arteries preventing a safe connection
Recipient:
1. Multi-organ transplantation
2. Planned dual kidney transplantation
3. The recipient is unable or unwilling to give informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Kidney graft function as measured by a 24-hour creatinine clearance at 1 year after transplantation
- Secondary Outcome Measures
Name Time Method