Skip to main content
MedPathMedPath Home
Clinical Trials/ISRCTN32967929
ISRCTN32967929
Completed
未知

A multicentre, double blind, randomised, parallel-group, paired trial to compare the effect of hypothermic machine perfusion preservation with and without the addition of oxygen in transplantation of Maastricht category III kidneys donated after circulatory death from donors aged 50 years or older

niversity of Oxford (UK)0 sites197 target enrollmentDecember 11, 2013
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsMachine perfusion preservation techniques of kidney graftsInjury, Occupational Diseases, Poisoning

Overview

Phase
未知
Intervention
Not specified
Conditions
Machine perfusion preservation techniques of kidney grafts
Sponsor
niversity of Oxford (UK)
Enrollment
197
Status
Completed
Last Updated
5 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2020 results in https://pubmed.ncbi.nlm.nih.gov/33220737/ (added 23/11/2020)

Registry
who.int
Start Date
December 11, 2013
End Date
June 30, 2018
Last Updated
5 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity of Oxford (UK)

Eligibility Criteria

Inclusion Criteria

  • •1\. All potential consecutive Maastricht category III DCD donors aged 50 years or older from the collaborating donor regions
  • •1\. At least 18 years old
  • •2\. Listed for renal transplantation due to end stage renal disease
  • •3\. Willingness to comply with the protocol procedures for the duration of the study

Exclusion Criteria

  • •1\. An aortic patch too small for a reliable connection
  • •2\. Too many renal arteries preventing a safe connection
  • •1\. Multi\-organ transplantation
  • •2\. Planned dual kidney transplantation
  • •3\. The recipient is unable or unwilling to give informed consent

Outcomes

Primary Outcomes

Not specified

Similar Trials

Completed
Phase 4
Evaluation of Lactosectan versus placebo to compare the effectiveness and safety in treating adult patients with intolerance to certain foods, primarily lactose intoleranceactose intoleranceNutritional, Metabolic, EndocrineLactose intolerance
ISRCTN18410689ovintethical Pharma SA60
Completed
Not Applicable
Metformin in Tuberous Sclerosis Complex
ISRCTN92545532niversity Hospitals Bristol NHS Foundation Trust (UK)55
Active, not recruiting
Phase 2
Effects of external trigeminal nerve stimulation in ADHD and mechanisms of actio
ISRCTN82129325King's College London150
Completed
Phase 3
Evaluation of the extended regimen versus standard regimen of oral contraceptive in premenstrual and/or menstrual symptoms
ISRCTN57661673IBBS Farmaceutica Ltd (Brazil)348
Completed
Not Applicable
A double-blind, multicentric, multinational randomised study to assess the effects of two years administration of 2 g per day of strontium ranelate versus bisphosphonate in women with postmenopausal osteoporosis on bone geometry and bone strength measured by peripheral-Quantitative Computed Tomography (p-QCT)
ISRCTN10335153Institut de Recherches Internationales Servier (France)80