Sensory Properties of Bowel Cleansing Solutions

Not Applicable

Completed

• Conditions: Laxative Bowel Cleansing Solutions
• Interventions: Behavioral: acceptability test; Behavioral: Descriptive analysis

• Registration Number: NCT02642783
• Lead Sponsor: American University of Beirut Medical Center

Brief Summary

Samples of 4 commercially available bowel cleansing solutions, namely PEG-electrolyte + ascorbic acid (PEG-Asc, Moviprep®, Norgine, UK), PEG-electrolyte (PEG, Fortrans® Ibsen, France), sodium picosulfate/magnesium citrate (SPS, Picoprep®, Ferring, Switzerland), and oral sodium sulfate (OSS, Izinova®, Ibsen, France) were prepared according to the manufacturer's instructions. Descriptive analysis was conducted with trained panelists (N= 14) to create a sensory profile for the solutions and generated attributes were rated on an unstructured 15-cm line scale using the Compusense at-hand® (Guelph, Canada) sensory evaluation software. Acceptability testing was carried out with untrained participants (N=80) and samples were rated on the 9-point hedonic scale. Moreover, a Just-About-Right (JAR) scale was included for the four basic tastes to determine their compatibility with optimum taste/acceptability levels in the products.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-11
• Status Verified: 2015-12
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Study First Submitted: 2015-12-22
• Study First Submitted QC: 2015-12-29
• Last Update Submitted: 2015-12-29
• Study First Posted: 2015-12-30
• Last Update Posted: 2015-12-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• age between 18 and 50 years

Exclusion Criteria

• allergies to polyethelene glycol (PEG), artificial sweeteners

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Acceptability test	acceptability test	panelists were asked to rate the acceptability of different laxative bowel cleansing solutions using the 9-point hedonic scale.
Descriptive analysis	Descriptive analysis	panelists were asked to rate different sensory attributes for different laxative bowel cleansing solutions on a 15 cm line scale.

Primary Outcome Measures

Name	Time	Method
rating of sensory attributes	3 weeks	participants attended 4 training sessions during which they generated sensory descriptive attributes specific for the tasted laxative solutions. In addition, they evaluated the laxative samples by rating generated attributes on a 15-cm unstructured line scale using compusense at-hand sensory evaluation software.

Secondary Outcome Measures

Name	Time	Method
Acceptability Score	1 week	untrained participants evaluated the laxative samples for acceptability testing using the 9-point hedonic scale.
Just about right score	1 week	Participants evaluated the laxative samples for the 4 basic tastes (saltiness, sourness, sweetness and bitterness) to determine their compatibility with optimum taste levels in the products.