A clinical trial to compare the effects of four drugs,oxytocin,misoprostol,15-methylprostaglandinF2alpha and methylergometrine in active management of third stage of labor.
Phase 3
Completed
- Conditions
- Health Condition 1: null- Labor
- Registration Number
- CTRI/2015/06/005918
- Lead Sponsor
- Maulana Azad Medical College Lok Nayak Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 1000
Inclusion Criteria
All non-high risk women at term pregnancy (37 to 40 weeks of gestation) who delivered vaginally. Ready to give written and informed consent
Exclusion Criteria
Placental disorders-abruption placentae/ marginal placenta previa/low lying placenta. malpresentation, instrumental delivery,grand multipara,prvious uterine scar,rh negative pregnancy,liquor abnormalities/chorioamnionitis,coagulation disorders,medical disorders-anaemia/diabetes/hypertension/heart disease asthma , epilepsy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To measure amount of blood lossTimepoint: 1. At the time of blood loss more than 500 ml
- Secondary Outcome Measures
Name Time Method 1.Duration of third stage of labor <br/ ><br>2.Change in hematocrit from predelivery to 24 hour postpartum <br/ ><br>3.Need for administration of other uterotonics and blood transfusion. <br/ ><br>4.Side effects and complications within 24 hour.Timepoint: 1.Duration of third stage more than 6 min <br/ ><br>2.Fall in hematocrit <br/ ><br>3.Additional use of other uterotonics. <br/ ><br>4. Side effects like nausea, hypertension, shivering,diarrhea.