The Feasibility and Safety of Optical Coherence Tomography Guided Thrombus Aspiration in Patients With Initial Conservative Management of Non-ST-Elevation Myocardial Infarction - OCT guided thrombus aspiration

niversitair Medisch Centrum Groningen0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年5月6日

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•- Chest pain suggestive for myocardial ischemia for at least 30 minutes,
•- Electrocardiogram (ECG) with ST- segment shifts (ST-segment depression >1 mm in at least two contiguous leads or transient ST-segment elevation >1 mm with duration of <30 min in at least two contiguous leads) and/or T-wave changes (T-wave inversion >1.5 mm in at least three contiguous leads),
•- Positive troponin T >0,04 µg/L.
•- Time between the onset of last symptoms and PCI of more than 12 hours and shorter than 7 days,
•- initial conservative management (e.g. asprin, heparine, statins)
•- The presence of one ischemia-related target lesion on invasive coronary angiography with a clinical indication for PCI,
•- TIMI flow grade of 2 or higher,
•- Vessel suitable for 2.25 mm diameter or larger stent implantation,
•- Informed consent.

•- Persistent ST-elevation of > 1 mm in 2 or more leads,
•- TIMI 0 or 1 flow on coronary angiography,
•- Need for emergency coronary artery bypass grafting,
•- Presence of cardiogenic shock,
•- Preexisting life-threatening disease with a life expectancy of less than 6 months,
•- Creatinine > 200 µmol/l before the procedure,
•- Inability to provide informed consent.

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