Gene expression profiling of healthy lymphoid precursor cells
Recruiting
- Conditions
- healthy volunteers
- Registration Number
- DRKS00023583
- Lead Sponsor
- niversitätsklinikum Schleswig-Holstein Campus Kiel
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Full legal age, absence of hematological diseases, no medication with possible interactions with haematopoeisis, no chronically inflammatory diseases
Exclusion Criteria
Underlying hematological diseases, medication with possible interactions with haematopoesis, chronically inflammatory diseases, probably difficult conditions for bone marrow puncture
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method This project aims to define the developmental origin of the different molecular subtypes of ALL and to identify leukemia-specific gene expression in contrast to gene regulation during normal lymphopoiesis. Characterization of the disease-specific gene regulation will guide us to explore oncogenic signaling dependencies as novel therapeutic targets.
- Secondary Outcome Measures
Name Time Method