Cost-effectiveness analysis of 2-octyl cyanoacrylate tissue adhesive and suture for closure of simple lacerations: Randomised Controlled Trial

Not Applicable

Completed

• Conditions: Simple laceration wound repair; Injury, Occupational Diseases, Poisoning; Simple laceration

• Registration Number: ISRCTN87805481
• Lead Sponsor: The Health and Health Services Research Fund (HHSRF) (Hong Kong)

Brief Summary

2009 results in: https://www.ncbi.nlm.nih.gov/pubmed/18440668 (added 17/05/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2006-07-31
• Study Start: 2007-08-24
• Last Update Posted: 27 May 2019

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 186

Inclusion Criteria

All patients aged greater than or equal to 18 years presenting to the ED between 9 am to 5 pm, Monday to Friday, with traumatic lacerations or incised wounds were eligible for the study.

Exclusion Criteria

To standardise the recruited cases for comparison, wounds with the following features were excluded:
1. Wound length greater than 8 cm
2. Deep wounds with muscle, tendon, bone, joint or neurovascular structure involvement
3. Scalp wounds
4. Vermilion border involvement at lip
5. Stellate lacerations
6. Stab wounds to the trunk or neck
7. Heavily contaminated or infected wounds
8. Animal or human bite
9. Wounds which required debridement of devitalised tissue
10. Wounds in which haemostasis could not be achieved within 20 minutes by direct pressure
11. Wounds greater than 12 hours old
12. We also excluded patients with a history of keloid formation or with physical or cognitive impairment making the use of visual analogue scales inaccurate

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome measure was the Cosmetic Visual Analogue Scale (CVAS) score, measured at baseline, day 14, 30 and 90.

Secondary Outcome Measures

Name	Time	Method
<br> Secondary outcome measures included:<br> 1. Visual Analogue Scale (VAS) score, measured at baseline, day 14, 30 and 90<br> 2. Wound Evaluation Scale (WES) score, measured at day 14<br> 3. Total time spent in each closure method<br> 4. The overall patients' satisfaction, measured at day 30<br> 5. The total costs required per patient in each method<br>