Ocular Hypertension Treatment Study (OHTS)

Completed

• Conditions: Ocular Hypertension; Glaucoma

• Registration Number: NCT00803998
• Lead Sponsor: The New York Eye & Ear Infirmary

Brief Summary

The Ocular Hypertension Treatment Study is a multi-center clinical trial sponsored by the National Eye Institute, designed to determine the efficacy and safety of topically administered eye lowering medication

Detailed Description

Not available

Study Timeline

• Study Start: 1994-02
• Study Completion: 2006-12
• Status Verified: 2008-12
• Study First Submitted: 2008-12-05
• Study First Submitted QC: 2008-12-05
• Study First Posted: 2008-12-08
• Last Update Submitted: 2013-10-31
• Last Update Posted: 2013-11-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Qualifying IOP in at least one eye of each participant must be more than or equal 24 mmHg but less than or equal to 32 mm HG calculated from two separate consecutive determination taken at least 2 hours, but not greater than 12 weeks apart.
• Normal and reliable 30-2 Humphrey Visual Fields in both eyes.
• Normal Optic disc in both eyes on clinical examinations and stereoscopic photographs as determined by the Optic Disc Reading Center.

Exclusion Criteria

• Visual acuity worse than 20/40 in either eye on qualifying exam.
• Previous intraocular surgery: laser trabeculoplasty, laser iridotomy, filtering surgery, combined cataract extraction/filtering procedures, penetrating keratoplasty and retinal detachment repair.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified