The Interaction Between Appetite Hormones and Their Importance for Maintenance of Weight Loss After a Low Calorie Diet
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 58
- 试验地点
- 4
- 主要终点
- Change in hormone level corrected for weight change
研究概览
简要总结
Glucagon Like Peptide (GLP) -1 affects metabolic response corrected for weight change
详细描述
Many obese people have had several successful weight losses, however very few can maintain the weight loss over a longer period (e.g. one year) Therefore, we want to investigate the metabolic response and the importance for maintenance of weight loss in obese people, who lost at least 7, 5 % body weight by low calorie diet followed by 52 weeks of diet weight maintenance with or without supplement of GLP-1.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI > 30 and < 40 (kg/m2)
排除标准
- •Other known illness
- •Medicine that affects glucose- and lipid metabolism, appetite or food intake
- •Pregnancy
- •Breast feeding
研究组 & 干预措施
GLP-1
GLP-1 and low calorie diet
干预措施: GLP-1 (Other)
GLP-1
GLP-1 and low calorie diet
干预措施: low calorie diet (Dietary Supplement)
Control
low calorie diet
干预措施: low calorie diet (Dietary Supplement)
结局指标
主要结局
Change in hormone level corrected for weight change
时间窗: Baseline and week 52
次要结局
未报告次要终点
研究者
Signe Torekov
Assistant professor
University of Copenhagen