The Interaction Between Appetite Hormones

Not Applicable

Completed

• Conditions: Obesity

• Registration Number: NCT02094183
• Lead Sponsor: University of Copenhagen

Brief Summary

Glucagon Like Peptide (GLP) -1 affects metabolic response corrected for weight change

Detailed Description

Many obese people have had several successful weight losses, however very few can maintain the weight loss over a longer period (e.g. one year) Therefore, we want to investigate the metabolic response and the importance for maintenance of weight loss in obese people, who lost at least 7, 5 % body weight by low calorie diet followed by 52 weeks of diet weight maintenance with or without supplement of GLP-1.

Study Timeline

• Study Start: 2011-09
• Study First Submitted: 2014-03-17
• Study First Submitted QC: 2014-03-20
• Study First Posted: 2014-03-21
• Primary Completion: 2014-04
• Study Completion: 2014-04
• Status Verified: 2014-07
• Last Update Submitted: 2014-07-04
• Last Update Posted: 2014-07-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

• BMI > 30 and < 40 (kg/m2)
• Healthy

Exclusion Criteria

• Other known illness
• Medicine that affects glucose- and lipid metabolism, appetite or food intake
• Pregnancy
• Breast feeding

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in hormone level corrected for weight change	Baseline and week 52

Trial Locations

Locations (2)

University of Copenhagen; 🇩🇰 Copenhagen, Denmark

Hvidovre University Hospital; 🇩🇰 Hvidovre, Denmark