Investigating the effect of using autologous amniotic membranes and fluid on wound healing and complications of cesarean surgery: a factorial randomized clinical trial

Tehran University of Medical Sciences0 个研究点目标入组 224 人开始时间: 待定最近更新: 2024年7月22日

适应症

试验速览

暂无简介。

•Age 18-45 years
•Singleton pregnancy
•Having a previous plan for cesarean section and elective cesarean section
•Planned gestational age of at least 36 weeks at the time of delivery
•Able to provide informed consent
•Intention to be available for the entire research period and to complete all relevant study steps, including follow-up visits and phone calls
•Hemoglobin above 10 g/dL at the time of hospitalization

•Body mass index greater than or equal to 40 at the time of entering the study
•Placenta previa or placenta accreta
•History of intestinal or urological surgery
•Multiple pregnancy
•Known or suspected impairment of immunological function, including infection with HIV, hepatitis B or C
•Use of immunosuppressive drugs, chemotherapy, radiotherapy, or taking systemic corticosteroids in the 4 weeks before surgery.
•Known tobacco or drug use
•Any condition that, in the opinion of the investigator, may pose a risk to the health of the participant or interfere with the evaluation of the study objectives
•History of keloid formation
•Participation in another clinical trial in the last three months
•Any serious cardiovascular, pulmonary, hepatic, renal, digestive, hematologic, endocrine, metabolic, neurological and psychological diseases
•Frequent vaginal examinations
•Emergency cesarean section
•Chorioamnionitis or other systemic infections at the time of presentation for caesarean section, including evidence of subabdominal skin infection (e.g. fungal infection)

发起方