Effect of amniotic membranes and fluid on cesarean surgery wound healing
- Conditions
- Cesarean surgical wound.Infection of obstetric surgical woundO86.0
- Registration Number
- IRCT20220408054454N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 224
Age 18-45 years
Singleton pregnancy
Having a previous plan for cesarean section and elective cesarean section
Planned gestational age of at least 36 weeks at the time of delivery
Able to provide informed consent
Intention to be available for the entire research period and to complete all relevant study steps, including follow-up visits and phone calls
Hemoglobin above 10 g/dL at the time of hospitalization
Body mass index greater than or equal to 40 at the time of entering the study
Placenta previa or placenta accreta
History of intestinal or urological surgery
Multiple pregnancy
Known or suspected impairment of immunological function, including infection with HIV, hepatitis B or C
Use of immunosuppressive drugs, chemotherapy, radiotherapy, or taking systemic corticosteroids in the 4 weeks before surgery.
Known tobacco or drug use
Any condition that, in the opinion of the investigator, may pose a risk to the health of the participant or interfere with the evaluation of the study objectives
History of keloid formation
Participation in another clinical trial in the last three months
Any serious cardiovascular, pulmonary, hepatic, renal, digestive, hematologic, endocrine, metabolic, neurological and psychological diseases
Frequent vaginal examinations
Emergency cesarean section
Chorioamnionitis or other systemic infections at the time of presentation for caesarean section, including evidence of subabdominal skin infection (e.g. fungal infection)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method