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Clinical Trials/NCT03997240
NCT03997240
Completed
Not Applicable

A Randomized Wait-list Control Trial Evaluating the Effect of Team-based Applied Clinical Neuroscience Care on Self-reported Symptoms of Depression and Cerebellar Function in Adults With Medication-resistant Depression

Life University1 site in 1 country20 target enrollmentJune 1, 2019
ConditionsDepression

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Depression
Sponsor
Life University
Enrollment
20
Locations
1
Primary Endpoint
P300 Auditory Evoked Potential task
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Pilot study design that operationalizes the multimodal manner of care while evaluating changes in depression symptoms, dysmetria, and balance for medication non-responders.

Detailed Description

Pilot study design that operationalizes the multimodal manner of care while evaluating changes in depression symptoms, dysmetria, and balance for medication non-responders. This research will provide an initial first step towards answering the following three research questions: 1. Does a multimodal chiropractic applied clinical neuroscience approach to care affect self-reported symptoms of depression? 2. Does a multimodal chiropractic applied clinical neuroscience approach to care affect dysmetria and balance control in a clinically depressed population? 3. Are changes in dysmetria and balance control correlated with a change in depressive symptoms.

Registry
clinicaltrials.gov
Start Date
June 1, 2019
End Date
July 11, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Life University
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • You are over the age of
  • You have been diagnosed with depression.
  • You are currently taking medication for depression or have previously taken medication.
  • You have been or were on your depression medication for at least 3 months.
  • You feel/felt that the medication is/was not helping.

Exclusion Criteria

  • Had a lifetime history of severe neurologic or mental illness (e.g. schizophrenia or substance abuse)
  • Are pregnant
  • Have pending litigation or a recent history of spinal fracture, metastatic cancer, chiropractic care within the past month
  • Present with contraindications to chiropractic care

Outcomes

Primary Outcomes

P300 Auditory Evoked Potential task

Time Frame: 20 minutes

Time-locked electroencephalography recording of the P300 event related potential. P300 testing involves placing electrodes on the participant's scalp while the individual is listening to a series to two different tones through headphones.

Secondary Outcomes

  • Shift Balance Platform(10 minutes)

Study Sites (1)

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