A Survey for Factors That Influence Postoperative Treatment Decision-making for Hepatocellular Carcinoma

• Conditions: Hepatocellular Carcinoma

• Registration Number: NCT04239781
• Lead Sponsor: Shanghai Zhongshan Hospital

Brief Summary

This is a non-interventional and questionnaire survey study. The investigators try to find out patient's willingness and expectation for post-operative treatments for hepatocellular carcinoma (HCC), as well as patients' willingness to participate in clinical trials using a questionnaire. The ultimate goal is to assist physicians in clinical treatment decision, clinical research, and government health and economic decision-making, as well as to help investigators understand how to increase public awareness of the HCC and the treatment course and efficacy of HCC, and the awareness of clinical trials.

Detailed Description

There is no world widely accepted adjuvant therapy for HCC and the guidelines from AASLD or EASL did not recommend any adjuvant therapy to prevent postoperative tumor recurrence of HCC. The goal of an adjuvant therapy is to meet the requirements of patients, which are influenced by many factors such as the strength of doctors' recommendation, economic affordability, tolerance of adverse reactions to treatment, and expectation of efficacy. Therefore, understanding patients' expectations for an adjuvant therapy after surgery will help doctors give more reasonable treatment. Participating in clinical trials is a new process of understanding and acceptance for each patient, so investigators try to understand the willingness and ideas of patients to participate in clinical trials, so as to provide more information for designing clinical trials and recruiting subjects for clinical trials.

The research was conducted through face-to-face interview, WeChat and telephone interview. For face-to-face interview and WeChat to participants, an informed consent should be signed.

Study Timeline

• Status Verified: 2020-01
• Study Start: 2020-01
• Study First Submitted: 2020-01-21
• Study First Submitted QC: 2020-01-21
• Last Update Submitted: 2020-01-21
• Study First Posted: 2020-01-27
• Last Update Posted: 2020-01-27
• Primary Completion: 2020-06
• Study Completion: 2020-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 2500

Inclusion Criteria

• Male or female aged 18 years or older;
• Confirmed diagnosis of HCC histologically or clinically;
• The participant must have received surgical resection;
• Ability to complete the questionnaire or independently or with the help of a friend, relative, or staff member of the oncology department.

Exclusion Criteria

• The patients that researchers consider not suitable to participate in this study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HCC patients' willingness and expectation for post-operative treatment.	6 months	Use questionnaires to understand the willingness and expectation of patients for post-operative treatment of hepatocellular carcinoma, as well as their willingness to participate in clinical trials.

Trial Locations

Locations (1)

Shanghai Zhongshan Hospital; 🇨🇳 Shanghai, China