Efficacy of Azadirachta Indica Based Herbal Mouthwash in Treating the Tooth Hypersensitivity

Not Applicable

Completed

• Conditions: Tooth Sensitivity
• Interventions: Diagnostic Test: Herbal based mouthwash

• Registration Number: NCT06288776
• Lead Sponsor: Pakistan Institute of Medical Sciences

Brief Summary

Type of study: Single-blinded clinical trial to evaluate the effectiveness of Azadirachta indica based Herbal mouthwash to treat the tooth sensitivity in patients.

Participants aged 20 years and above having Gingival Index score 3 will be included in the study. Their tooth sensitivity will be checked initially and then they will be given Herbal based mouthwash for 3 months. Again, their tooth sensitivity shall be checked after 3 months.

Detailed Description

In this study Herbal based mouthwash will be evaluated for eliminating the tooth sensitivity in the participants having Gingival Index score 3 with VAS scores for sensitivity ranging between 30-80 . Consecutive non-random sampling technique will be used in this study where Participants included will be assessed for tooth sensitivity through Visual Analogue Scale (VAS) initially for base line readings. These participants will be given Azadirachta indica based Herbal mouthwash for three months and then again their tooth sensitivity will be assessed by Visual Analogue Scale (VAS) for final readings. The mean values of VAS scoring both before and after the usage of herbal mouth wash will be compared to investigate the clinical efficacy of this mouthwash in treating the tooth sensitivity.

Study Timeline

• Study Start: 2023-02-01
• Primary Completion: 2023-04-30
• Study Completion: 2023-04-30
• Status Verified: 2024-02
• Study First Submitted: 2024-02-24
• Study First Submitted QC: 2024-02-24
• Last Update Submitted: 2024-02-24
• Study First Posted: 2024-03-01
• Last Update Posted: 2024-03-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Patients with good general health and no allergy
• Patients who have not used any mouthwash in last 3 month
• Study teeth shall be free of decay and restoration
• Study teeth shalll not be mobile
• Study teeth shall have the Gingival Index score 3
• Participants shall be able to read ,write and willing to give consent.

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Exclusion Criteria

• Patients with poor general health and allergies
• Patients who have used any mouthwash in last 3 months
• Teeth with decay and restorations
• Teeth with mobility
• Teeth with Gingival Index score more than 3
• Participants that wonn't be able to read ,write and willing to give consent.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Interventional Group	Herbal based mouthwash	Participants will be assessed for their tooth sensitivity (VAS scoring) and after giving herbal based mouthwash sensitivity will be assessed after 3 months

Primary Outcome Measures

Name	Time	Method
Toothsensitivity declination with herbal based mouthwash	3 months	Evaluation of herbal based mouth wash in eliminating the tooth sensitivity ranging between VAS scores 30-80.

Trial Locations

Locations (1)

Afsheen Mansoor; 🇵🇰 Islamabad, Pakistan