NL-OMON34866已完成不适用
Post-Treatment Effects of Dipyridamole On Nucleoside Transport Inhibition - Post-treatment dipyridamole
Pharmacology-Toxicology0 个研究点目标入组 14 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 14
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •Healthy volunteers
- •Written informed consent
排除标准
- •History of any cardiovascular disease
- •Hypertension (in supine position: systole>140 mm Hg, diastole>90 mmHg)
- •Diabetes mellitus (fasting glucose >7.0 mmol/L or random glucose>11.0 mmol/L)
- •Concomitant use of medication
- •Alcohol or drug abuse
- •Women without appropriate anticonception
- •Participation to any drug-investigation during the previous 60 days as checked with VIP check
研究者
相似试验
已完成
不适用
The effects of oral dipyridamole treatment on the innate immune response during human endotoxemia.Blood poisoning1000401810011954sepsisNL-OMON34679niversitair Medisch Centrum Sint Radboud30
尚未招募
4 期
Does short dipyridamole administration induce protection against ischemia-reperfusion injury?infarctionischemia reperfusion injury1001108210003216NL-OMON31190niversitair Medisch Centrum Sint Radboud10
进行中(未招募)
1 期
The effect of dipyridamole on the pharmacokinetics of metformin.The antihyperglycemic drug metformin and the thrombocyte aggregation inhibitor dipyridamole are often used concomitantly in patients with diabetes who have suffered a transient ischemic attack or stroke. Gastrointestinal absorption of metformin is mediated by the equilibrative nucleoside transporter 4 (hENT4). Dipyridamole has been reported to inhibit hENT4 transport in vitro. Dipyridamole may therefore negatively influence the uptake of metformin from the gastrointestinal tract.MedDRA version: 14.1Level: PTClassification code 10068071Term: Inhibitory drug interactionSystem Organ Class: 10018065 - General disorders and administration site conditionsMedDRA version: 14.1Level: PTClassification code 10013710Term: Drug interactionSystem Organ Class: 10018065 - General disorders and administration site conditionsEUCTR2012-000363-24-NLRadboud University Medical Centre Nijmegen18
招募中
4 期
The effect of dipyridamole on the pharmacokinetics of metformin.geneesmiddeleninteractieDrug interactionNL-OMON37582niversitair Medisch Centrum Sint Radboud18
撤回
2 期
The role of Dipyridamole in Improving the False Negative Rate in Pre-Operative Parathyroid Adenoma Localisation Using 99mTc SestamibiParathyroid AdenomaACTRN12605000153617Robert Williams20
