Inflammatory Response as a Prognostic Factor of Recurrence of Atrial Fibrillation After Ablation

• Conditions: Atrial Fibrillation

• Registration Number: NCT02844959
• Lead Sponsor: Medical University of Warsaw

Brief Summary

The aim of this study is to evaluate inflammatory response as a prognostic factor of atrial fibrillation recurrency after ablation. Inflammatory response will be assessed by double measurement of C-reactive protein, fibroblast growth factor 2 (FGF2), matrix metallopeptidase 8 (MMP8) and body temperature. Dynamics of change of troponin I will be measured additionally.

After ablation each patient will be monitored with ECG telemonitoring system for 7 days.

Detailed Description

Not available

Study Timeline

• Status Verified: 2016-07
• Study Start: 2016-07
• Study First Submitted: 2016-07-22
• Study First Submitted QC: 2016-07-25
• Last Update Submitted: 2016-07-25
• Study First Posted: 2016-07-26
• Last Update Posted: 2016-07-26
• Primary Completion: 2017-07
• Study Completion: 2018-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• signed consent;
• criteria for ablation of atrial fibrillation.

Exclusion Criteria

• previous pulmonary veins isolation;
• ablation other than pulmonary veins isolation during the procedure;
• atrial fibrillation at the beginning of ablation procedure;
• usage of 'single shot' devices.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Atrial fibrillation within the first 7 days after ablation	within the first 7 days after ablation

Secondary Outcome Measures

Name	Time	Method
Atrial fibrillation within 6 months after ablation	6 months

Trial Locations

Locations (1)

1st Department of Cariology of Medcial University of Warsaw; 🇵🇱 Warsaw, Mazowieckie, Poland