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Clinical Trials/NCT02844959
NCT02844959
Unknown
Not Applicable

Assessment of Course of Inflammatory Biomarkers Concentrations After Pulmonary Veins Isolation as a Prognostic Factor of Atrial Fibrillation Treatment Effectiveness (ACtIVE-AF Study)

Medical University of Warsaw1 site in 1 country120 target enrollmentJuly 2016
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ConditionsAtrial Fibrillation

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Atrial Fibrillation
Sponsor
Medical University of Warsaw
Enrollment
120
Locations
1
Primary Endpoint
Atrial fibrillation within the first 7 days after ablation
Last Updated
9 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The aim of this study is to evaluate inflammatory response as a prognostic factor of atrial fibrillation recurrency after ablation. Inflammatory response will be assessed by double measurement of C-reactive protein, fibroblast growth factor 2 (FGF2), matrix metallopeptidase 8 (MMP8) and body temperature. Dynamics of change of troponin I will be measured additionally.

After ablation each patient will be monitored with ECG telemonitoring system for 7 days.

Registry
clinicaltrials.gov
Start Date
July 2016
End Date
July 2018
Last Updated
9 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Medical University of Warsaw
Responsible Party
Principal Investigator
Principal Investigator

Marcin Grabowski

Clinical Professor, Marcin Grabowski, Medical University of Warsaw

Medical University of Warsaw

Eligibility Criteria

Inclusion Criteria

  • •signed consent;
  • •criteria for ablation of atrial fibrillation.

Exclusion Criteria

  • •previous pulmonary veins isolation;
  • •ablation other than pulmonary veins isolation during the procedure;
  • •atrial fibrillation at the beginning of ablation procedure;
  • •usage of 'single shot' devices.

Outcomes

Primary Outcomes

Atrial fibrillation within the first 7 days after ablation

Time Frame: within the first 7 days after ablation

Secondary Outcomes

  • Atrial fibrillation within 6 months after ablation(6 months)

Study Sites (1)

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