CASE SERIES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS DIAGNOSED IN TWO HOSPITALS OF THE TERTIARY LEVEL OF CARE OF THE COSTA RICAN SOCIAL SECURITY Fund, 2017-2018
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 137
- 试验地点
- 1
- 主要终点
- Clinical manifestations of all adult patients diagnosed with primary and idiopathic immune defects
研究概览
简要总结
Primary immunodeficiencies represent a underdiagnosed group of rare diseases which if diagnosed well and in time can be treated in an efficient manner and prevent complications that may affect the quality of patients life in an severe manner. Neither in Costa Rica nor in Central America studies or national registries regarding the prevalence and characterization of primary immunodeficiencies in adult patients exist up to now. This study reflects for the first time the epidemiologic situation of primary immunodeficiencies in a Central American country, characterizing adult patients diagnosed with primary and idiopathic immune disorders treated in two specialized immunodeficiency clinics in Costa Rica.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 12 Years 至 100 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients from adult primary immunodeficiency clinics will be included.
排除标准
- •Patients with HIV
- •Proven secondary immunodeficiencies.
结局指标
主要结局
Clinical manifestations of all adult patients diagnosed with primary and idiopathic immune defects
时间窗: 1 year
Describe the clinical manifestations of all adult patients diagnosed with primary and idiopathic immune defects attended in the primary immunodeficiency clinics of the Hospitals Mexico and Dr. Rafael Ángel Calderón Guardia during the study period.
次要结局
- Concordances between clinical manifestations and literature(1 year)
- organic complications(1 year)
- characterization of immunodeficient patients(1 year)
- type and degree of immunodeficiency(1 year)
- pathonges that cause infectious(1 year)
- bacteria present in upper airways(1 year)