Primary Immunodeficiencies in Costa Rican Adults

Completed

• Conditions: Primary Immune Deficiency in Adults

• Registration Number: NCT04963660
• Lead Sponsor: Caja Costarricense de Seguro Social

Brief Summary

Primary immunodeficiencies represent a underdiagnosed group of rare diseases which if diagnosed well and in time can be treated in an efficient manner and prevent complications that may affect the quality of patients life in an severe manner. Neither in Costa Rica nor in Central America studies or national registries regarding the prevalence and characterization of primary immunodeficiencies in adult patients exist up to now. This study reflects for the first time the epidemiologic situation of primary immunodeficiencies in a Central American country, characterizing adult patients diagnosed with primary and idiopathic immune disorders treated in two specialized immunodeficiency clinics in Costa Rica.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-11-11
• Primary Completion: 2019-11-11
• Study Completion: 2019-11-11
• Status Verified: 2021-07
• Study First Submitted: 2021-07-06
• Study First Submitted QC: 2021-07-14
• Last Update Submitted: 2021-07-14
• Study First Posted: 2021-07-15
• Last Update Posted: 2021-07-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 137

Inclusion Criteria

• All patients from adult primary immunodeficiency clinics will be included.

Exclusion Criteria

• Patients with HIV
• Proven secondary immunodeficiencies.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical manifestations of all adult patients diagnosed with primary and idiopathic immune defects	1 year	Describe the clinical manifestations of all adult patients diagnosed with primary and idiopathic immune defects attended in the primary immunodeficiency clinics of the Hospitals Mexico and Dr. Rafael Ángel Calderón Guardia during the study period.

Secondary Outcome Measures

Name	Time	Method
Concordances between clinical manifestations and literature	1 year	•Establish concordances between the clinical manifestations of the group of patients under study with those described in the literature according to the different pathologies.
organic complications	1 year	Record organic complications secondary to immunodeficiency status.
characterization of immunodeficient patients	1 year	Characterize immunodeficient patients using sociodemographic and health variables.
type and degree of immunodeficiency	1 year	Differentiate the type and degree of immunodeficiency of each patient.
pathonges that cause infectious	1 year	Report isolated pathogens that cause infectious manifestations in patients.
bacteria present in upper airways	1 year	•Report the colonizing bacteria present in the cultures of the upper airways of the patients requested in the initial approach.

Trial Locations

Locations (1)

Hospital Calderon Guardia; 🇨🇷 San José, Costa Rica