NCT04351893已完成不适用
Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 935
- 试验地点
- 9
- 主要终点
- Identify Genetic Variants
研究概览
简要总结
The CAUSE study is a multicenter study, with domestic (n=4) and international (n=6) study sites. Children and young adults (ages 0-18) who have microtia and/or craniofacial microsomia and their parents are invited to participate. Children and parents are asked to provide a DNA sample (blood or saliva) and are asked to upload a few photos of their face. Parents are asked a short interview. Participants are able to participate from home or at one of four domestic sites.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 0 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Identify Genetic Variants
时间窗: Through study completion, an average of 1 year.
To identify genetic variants related to the CFM spectrum using whole genome sequencing
次要结局
- Characterize phenotype(Through study completion, an average of 1 year.)
- Characterize markers(Through study completion, an average of 1 year.)
- Coding and non-coding variants(Through study completion, an average of 1 year.)
研究者
Carrie Heike
Professor
Seattle Children's Hospital
研究点 (9)
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