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Clinical Trials/CTRI/2025/07/091141
CTRI/2025/07/091141RecruitingNot Applicable

“COMPARATIVE EVALUATION OF EFFICACY OF 2 percent HYALURONIC ACID GEL AND INJECTABLE PLATELET RICH FIBRIN IN TREATMENT OF INTERDENTAL PAPILLARY RECESSION OF MAXILLARY ANTERIOR TEETH – A RANDOMIZED CONTROL TRIAL”

DrSuyog C S1 site in 1 country90 target enrollmentStarted: July 30, 2025Last updated:
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Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Sponsor
Enrollment
90
Locations
1
Primary Endpoint
satisfactory papillary fill
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

All the patients will undergo scaling and root planing and randomly alloted into 3 groups i.e, hayaluronic acid group, injectable-platelet rich fibrin group, control group. 2% hyaluronic acid is injected in the desired area and repeated on 21st, 42nd day. In the i-PRF group is injected on baseline and 11th, 22nd day. The control group only scaling and root planing is done

Study Design

Study Type
Interventional
Allocation
Coin toss, Lottery, toss of dice, shuffling cards etc
Masking
Participant Blinded

Eligibility Criteria

Ages
18.00 Day(s) to 40.00 Day(s) (—)
Sex
All

Inclusion Criteria

  • •Systemically healthy individuals of age groups ranging from 18 years to 40 years.
  • •Patients with interdental papilla recession of class I and class II in the maxillary anterior teeth.
  • •(Norldand and Tarnow)
  • •Patients with otherwise good periodontal health and oral hygiene with full mouth bleeding on probing index score less than 15%.
  • •Patients with no interdental bone loss as seen in an IOPA x-ray.

Exclusion Criteria

  • •Patients who have undergone surgical periodontal therapy less than six months before the study.
  • •Patients with malocclusion or midline diastema or aberrant frenal attachment or those undergoing active orthodontic therapy.
  • •Smokers and tobacco chewers.
  • •Patients taking drugs that cause gingival inflammation and enlargement.
  • •Pregnancy and lactating women.

Outcomes

Primary Outcomes

satisfactory papillary fill

Time Frame: baseline, three months and six months

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
DrSuyog C S
Sponsor Class
Research institution and hospital
Responsible Party
Principal Investigator
Principal Investigator

Dr.Suyog C S

Sharavathi Dental College and Hospital

Study Sites (1)

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