A Cohort Study on Biomarkers of Hypertension in Guangdong Province(GDP Study)

Recruiting

• Conditions: Hypertension; Cardiovascular Diseases

• Registration Number: NCT04212455
• Lead Sponsor: Guangdong Provincial People's Hospital

Brief Summary

Hypertension is the most common chronic diseases and a most important risk factor for cardiovascular and cerebrovascular diseases, and also a substantial public health problem. The purpose of the study is to investigate the association between biomarkers and adverse outcomes in patients with hypertension.

Detailed Description

Study population includes subjects who are hypertension, of any race or ethnicity, 18 or older years of age, and have provided written informed consent to provide whole blood specimens at one or more study visits.

Physical examination, questionnaire survey and biological sample collection will be conducted at baseline and the incidence of all-cause and cardiovascular mortality will be investigated during follow-up.

Study Timeline

• Status Verified: 2019-12
• Study First Submitted: 2019-12-24
• Study First Submitted QC: 2019-12-24
• Study First Posted: 2019-12-27
• Study Start: 2020-01-01
• Last Update Submitted: 2020-01-10
• Last Update Posted: 2020-01-13
• Primary Completion: 2022-12-31
• Study Completion: 2050-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50000

Inclusion Criteria

• ≥18 years old
• In accordance with the diagnosis of hypertension (including Blood pressure ≥140/90mmHg and/or taking antihypertensive drugs and/or self-reported hypertension)

Exclusion Criteria

• <18 years old
• Unsigned informed consent
• Pregnant Women and Lactation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All-Cause Mortality	From date of inclusion until the date of death from any cause, assessed up to 1 year	All-cause mortality was confirmed through a combination of hospital medical records, telephone contacts with patients or family members, and death registration at the Guangdong Provincial Center for Disease Control and Prevention.

Secondary Outcome Measures

Name	Time	Method
Cardiovascular Mortality	From date of inclusion until the date of death from any cause, assessed up to 1 year	Cardiovascular mortality was defined as death attributable to an ischemic cardiovascular cause (including fatal MI, stroke).

Trial Locations

Locations (2)

Guangdong Provincial People's Hospital; 🇨🇳 Guangzhou, Guangdong, China

Guangdong Cardiovascular Institute; 🇨🇳 Guangzhou, Guangdong, China