Establishing Biobank in a Cohort Study for Hypertensive Patients in Guangdong Province(GDP Study)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hypertension
- Sponsor
- Guangdong Provincial People's Hospital
- Enrollment
- 50000
- Locations
- 2
- Primary Endpoint
- All-Cause Mortality
- Status
- Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
Hypertension is the most common chronic diseases and a most important risk factor for cardiovascular and cerebrovascular diseases, and also a substantial public health problem. The purpose of the study is to investigate the association between biomarkers and adverse outcomes in patients with hypertension.
Detailed Description
Study population includes subjects who are hypertension, of any race or ethnicity, 18 or older years of age, and have provided written informed consent to provide whole blood specimens at one or more study visits. Physical examination, questionnaire survey and biological sample collection will be conducted at baseline and the incidence of all-cause and cardiovascular mortality will be investigated during follow-up.
Investigators
Eligibility Criteria
Inclusion Criteria
- •≥18 years old
- •In accordance with the diagnosis of hypertension (including Blood pressure ≥140/90mmHg and/or taking antihypertensive drugs and/or self-reported hypertension)
Exclusion Criteria
- •\<18 years old
- •Unsigned informed consent
- •Pregnant Women and Lactation
Outcomes
Primary Outcomes
All-Cause Mortality
Time Frame: From date of inclusion until the date of death from any cause, assessed up to 1 year
All-cause mortality was confirmed through a combination of hospital medical records, telephone contacts with patients or family members, and death registration at the Guangdong Provincial Center for Disease Control and Prevention.
Secondary Outcomes
- Cardiovascular Mortality(From date of inclusion until the date of death from any cause, assessed up to 1 year)