Attention Bias Modification Treatment (ABMT) for Patients With Post Traumatic Stress Disorder (PTSD)

Phase 2

Completed

• Conditions: Attention Bias Modification Treatment (ABMT)
• Interventions: Behavioral: Attention Bias Modification Treatment (ABMT)

• Registration Number: NCT01368302
• Lead Sponsor: Tel Aviv University

Brief Summary

Patients with Post Traumatic Stress Disorder (PTSD) will be randomly assigned to either Attention Bias Modification Treatment (ABMT) designed to normalize threat-related attention biases or a placebo control condition not designed to change attention patterns. Outcome measures will be Post Traumatic Stress Disorder (PTSD), depression, and anxiety symptoms as measured by gold standard questionnaires and symptom counts derived from structured clinical interviews.

We expect to see significant Post Traumatic Stress Disorder symptom reduction in the Attention Bias Modification Treatment (ABMT) group relative to the placebo control group in which no symptomatic relief is expected.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-05-31
• Study First Submitted QC: 2011-06-06
• Study First Posted: 2011-06-07
• Study Start: 2011-07
• Primary Completion: 2013-03
• Study Completion: 2013-03
• Status Verified: 2014-12
• Last Update Submitted: 2014-12-01
• Last Update Posted: 2014-12-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 52

Inclusion Criteria

• Combat-related PTSD diagnosis

Exclusion Criteria

• Other treatment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Attention Bias Modification (ABM)	Attention Bias Modification Treatment (ABMT)	Attention training via repeated trials of a dot-probe task intended to normalize threat-related attention biases.
Placebo	Attention Bias Modification Treatment (ABMT)	Attention training via repeated trials of a dot-probe task not intended to change threat-related attention patterns.

Primary Outcome Measures

Name	Time	Method
Clinician-Administered PTSD Scale (CAPS)	40 minutes	The clinician-Administered PTSD Scale (CAPS) is a 30-item structured interview that corresponds to the DSM-IV criteria for PTSD (Blake, Weathers, Nagy, Kaloupek, Charney, \& Keane, 1995).

Secondary Outcome Measures

Name	Time	Method
PTSD Check List (PCL)	10 minutes	Post-traumatic Stress symptoms will be evaluated using the 17-item National Center for PTSD Checklist of the Department of Veterans Affairs- PCL (Blanchard, Jones-Alexander, Buckley, \& Forneris, 1996; Hoge, 2004; Kang, Natelson, Mahan, Lee, \& Murphy, 2003).

Trial Locations

Locations (1)

Tel Aviv University; 🇮🇱 Tel Aviv, Israel