The Optimization of Medications in Chronic Heart Failure Using a Website
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- University of Michigan
- Enrollment
- 3
- Locations
- 1
- Primary Endpoint
- The change in medications will be measured by the Evidence Based Medicine Percent Score (EBMPS).
Study Overview
Brief Summary
Heart failure (HF) is the most common hospital discharge diagnosis among older adults in the United States. Strikingly, 2 in 5 patients are readmitted within 1-year following their first HF admission. This results in significant potentially avoidable costs to our already strained healthcare system since hospitalizations result in 70% of yearly HF management costs. One of the most common causes of readmission is lack of medication optimization. This study will determine the effectiveness of a medication optimization website.
Detailed Description
In a prospective design, 100 patients will be randomized to the intervention or usual care in a 1:1 fashion. Patients randomized to the intervention will receive an evidence-based medication recommendation intervention. Outcome measures will be collected at baseline and at 2 weeks post-intervention.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Health Services Research
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •left ventricular ejection fraction (LVEF) </= 40%
Exclusion Criteria
- •pregnancy
- •active cancer with a life expectancy less than 12 months
- •chronic inotropic therapy
Arms & Interventions
Medication Optimization Group
Patients randomized to the medication optimization group will receive an evidence-based medication recommendation intervention.
Intervention: Med Optimization Arm (Other)
Control Group
Patients in the control group will receive the same intervention, delayed 2 weeks after the intervention group. During those initial 2 weeks they will act as a control.
Outcomes
Primary Outcomes
The change in medications will be measured by the Evidence Based Medicine Percent Score (EBMPS).
Time Frame: Change over 2 weeks
The Evidence Based Medicine Percent Score (EBMPS) is calculated by the medications and doses the patient is taking (in points) divided by the total eligible medications based on the evidence (in points).
Secondary Outcomes
No secondary outcomes reported
Investigators
Michael Dorsch
Assistant Professor of Clinical Pharmacy
University of Michigan