Treatment of refractory depression using NeuroStar TMS Therapy System and a predictor of the treatment response: a comprehensive, exploratory study through neurobiological, neurophysiological, and neuroimaging approaches
Not Applicable
- Conditions
- Major depressive disorder
- Registration Number
- JPRN-UMIN000007611
- Lead Sponsor
- Department of Neuropsychiatry, Kyorin University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1. Psychotic episode, bipolar disorder, OCD, PTSD, eating disorder 2. Previous treatment with ECT, TMS, VNS, DBS, tDCS 3. Pregnancy 4. Personal or close family history of seizure disorder 5. Neurologic disorder, organic brain disease 6. Substance or alcohol dependence 7. Ferromagnetic material in body or close to head 8. Severe metabolic disease, endocrine disease 9. Active suicide idea 10. Taking medications known to lower seizure threshold
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HAMD 17, HAMD 24, MADRS Severity of depression is rated with these scales every 2 weeks.
- Secondary Outcome Measures
Name Time Method CGI, YMRS