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Acute Kidney Injury in Neonates at NICU in Assiut University Children Hospital Descriptive Study

Conditions
Neonatal Acute Kidney Injury
Registration Number
NCT03528837
Lead Sponsor
Assiut University
Brief Summary

Acute kidney injury (AKI) is a complex disorder with clinical manifestations ranging from mild dysfunction to complete anuric kidney failure. Its leads to sudden and rapid decline in renal excretory function within hours to days,accompanied by accumulation of nitrogenous waste products such creatinine,urea and other clinically un measured products

Detailed Description

Acute kidney injury (AKI) is an under-recognized morbidity of neonates; the incidence remains unclear due to the absence of a unified definition of AKI in this population and because previous studies have varied greatly in screening for AKI with serum creatinine and urine output assessments. Premature infants may be born with less than half of the nephrons compared with term neonates, predisposing them to chronic kidney disease (CKD) early on in life and as they age. AKI can also lead to CKD, and premature infants with AKI may be at very high risk for long-term kidney problems. AKI in neonates is often multifactorial and may result from prenatal, perinatal, or postnatal insults as well as any combination thereof.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
30
Inclusion Criteria
  • All cases of acute kidney injury in neonates who will be admitted to NICU Assiut University Children Hospital during the duration of the study.
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Exclusion Criteria
  • Cases with chronic renal affection Any case with congenital anomalies
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Diagnosed as acute kidney injury10-21 days

Diagnosis of acute kidney injury

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Assiut university children hospital

🇪🇬

Assiut, Egypt

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