Acute Kidney Injury in Neonates at NICU in Assiut University Children Hospital Descriptive Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Neonatal Acute Kidney Injury
- Sponsor
- Assiut University
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Diagnosed as acute kidney injury
- Last Updated
- 7 years ago
Overview
Brief Summary
Acute kidney injury (AKI) is a complex disorder with clinical manifestations ranging from mild dysfunction to complete anuric kidney failure. Its leads to sudden and rapid decline in renal excretory function within hours to days,accompanied by accumulation of nitrogenous waste products such creatinine,urea and other clinically un measured products
Detailed Description
Acute kidney injury (AKI) is an under-recognized morbidity of neonates; the incidence remains unclear due to the absence of a unified definition of AKI in this population and because previous studies have varied greatly in screening for AKI with serum creatinine and urine output assessments. Premature infants may be born with less than half of the nephrons compared with term neonates, predisposing them to chronic kidney disease (CKD) early on in life and as they age. AKI can also lead to CKD, and premature infants with AKI may be at very high risk for long-term kidney problems. AKI in neonates is often multifactorial and may result from prenatal, perinatal, or postnatal insults as well as any combination thereof.
Investigators
Mohammed Ali Abdelrhman
Resident of neonatology
Assiut University
Eligibility Criteria
Inclusion Criteria
- •All cases of acute kidney injury in neonates who will be admitted to NICU Assiut University Children Hospital during the duration of the study.
Exclusion Criteria
- •Cases with chronic renal affection Any case with congenital anomalies
Outcomes
Primary Outcomes
Diagnosed as acute kidney injury
Time Frame: 10-21 days
Diagnosis of acute kidney injury