To compare pain relief after giving analgesic injections using dexamethasone as additive to ropivacaine vs plain ropivacaine in chest wall muscle layers in patients undergoing breastsurgery.
Phase 3
Completed
- Conditions
- Health Condition 1: C509- Malignant neoplasm of breast of unspecified siteHealth Condition 2: C509- Malignant neoplasm of breast of unspecified site
- Registration Number
- CTRI/2021/03/031781
- Lead Sponsor
- Dr Porika Prashanth Nayak
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 64
Inclusion Criteria
1)Female patients aged 18 years and above
2)Posted for unilateral elective MRM
3)Belonging to American society of Anaesthesiologists (ASA) grade I, II, III
Exclusion Criteria
1)Patients refusal.
2)Contraindications to regional anesthesia (RA) (bleeding diathesis, infection at the site of block and peripheral neuropathy).
3)Allergy to study drugs.
4)BMI � 35 kg/m2 or body weight � less than 40kg.
5)Chest wall deformity.
6)Patients who have undergone prior breast surgery.
7)Psychiatric patients.
8)Pregnant and lactating patients.
9)Any untoward major intra-operative complication (if any). (severe hypotension, bradycardia any injury to the nerve related to the block)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total opioid consumption till 12 hours post-operatively.Timepoint: 0 hours(when patient arrived at post-operative care unit), 2 hours, 4 hours, 6 hours and 12 hours
- Secondary Outcome Measures
Name Time Method 1)Difference in pain scores post-operatively in first 12 hours using numeric rating scale (NRS). <br/ ><br>2)Post-operative sedation scores. <br/ ><br>3)Incidence and severity of post-operative nausea and vomiting (PONV). <br/ ><br>4)Other adverse events (if any). <br/ ><br>Timepoint: 0 hours, 2 hours, 4 hours, 6 hours, 12 hours post-operatively.