To evaluate the feasibility and impact of a home based preoperative exercise and Nutrition intervention in patients with high liver frailty index on post liver transplant outcomes - a prospective interventional Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- To assess survival following liver transplantation
研究概览
简要总结
Liver fraility index (LFI) assessment will be performed by the physiotherapist routinely for all liver transplant recipients as part of pre transplant evaluation. Patients with LFI above 4.0 will be enrolled in the study at the point of first contact. Dietary and exercise plan will be formulated as per the patient needs and capacity respectively. The patients will be educated regarding the need for the nutritional and exercise interventions. Fornightly compliance check will be performed telephonically or in person. Repeat assessment of LFI will be done a day prior to transplant. Post transplantation, limb and chest physiotherapy will commence from postoperative day 1 and dietician review will be taken once feeding can be started. During the time of discharge further dietary plans and exercise regimen will be provided to the patients. At the end of 3 months further review of nutritional status, functional capacity, LFI and quality of life will be done. Quality of life will be assessed repeated at the end of one year post transplantation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- All
入选标准
- •All patient with chronic liver disease undergoing evaluation for liver transplantation with LFI above 4.8 at the institute would be considered for inclusion.
排除标准
- •1.Patient not giving consent for the study or unable to give consent 2.Age ≤ 18y 3.Patients with acute liver failure
- •Patients in ICU for 2 weeks/ICU admission in past 2 weeks 5.Re transplantation Not likely for follow up at the study centre.
结局指标
主要结局
To assess survival following liver transplantation
时间窗: 3 months
次要结局
- To assess immediate postoperative recovery outcomes(2. To assess functional performance at the end of 3 months)
研究者
Dr Susan Paulin
Dr. Rela Institute and medical centre
