Thrombectomy in ST Elevation Myocardial Infarction, an Individual Patient Meta-analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18,000
- 主要终点
- Occurrence of Cardiovascular death
研究概览
简要总结
During primary percutaneous coronary intervention, distal embolization of thrombus and impaired microvascular perfusion has been associated with an increased mortality. Thrombectomy devices during primary percutaneous coronary intervention may prevent distal embolization by reducing thrombus burden and thus improve microvascular perfusion and reduce mortality.
详细描述
An individual patient meta-analysis of large randomized controlled trials comparing manual thrombectomy versus percutaneous coronary intervention alone in patients with ST elevation myocardial infarction will provide significantly more power to detect differences in mortality as well as important but rare events such as stroke and to assess benefits in pre-defined subgroups.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Randomized controlled trials comparing manual thrombectomy vs. percutaneous coronary intervention alone in patients with ST elevation myocardial infarction published between January 1980 and April
- •Large trials randomizing more than 1000 patients.
- •Trials must have had at least 30 day follow up.
排除标准
- 未提供
结局指标
主要结局
Occurrence of Cardiovascular death
时间窗: up to 30 days
time to event analysis
次要结局
- Occurrence of Cardiovascular death(up to 180 days)